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Take your statin drug . . . or else


It’s surprising that so many individuals are bullied by docs into taking statin ldl cholesterol medicine: “The proof is overwhelming: statins save lives.” “You’re a strolling time-bomb. I can’t be chargeable for your security if you happen to don’t take it.” “Your ldl cholesterol is so excessive that you may die of a coronary heart assault any time.” I’ve even heard of many sufferers being “fired” by docs due to a refusal to take the prescription for Lipitor, Zocor, Crestor, or different drug.

Why such strong-arm techniques? A number of causes:

  • Individuals are given the incorrect food plan, a food plan—decreased in complete and saturated fats, elevated “wholesome complete grains”—that causes irritation/rise in c-reactive protein (CRP), a drop in HDL (“good”) ldl cholesterol , rise in triglycerides, and an explosion of small LDL particles, all witnessed on an ordinary ldl cholesterol panel as low HDL, excessive triglycerides, and better LDL ldl cholesterol (although under-representing the total magnitude of rise in small LDL particles), in addition to greater fasting blood sugar, greater HbA1c, greater blood strain. These metabolic distortions improve cardiovascular threat, although not for the explanations most docs suppose. That is interpreted by most docs as reflecting your dangerous dietary habits and/or the overall uselessness of food plan.
  • The medical research purporting to point out 25-50% discount in cardiovascular threat do nothing of the type. The true profit is round 1-3% discount, at finest—measurable however small (and never in all teams of individuals, with small advantages confined principally to individuals who have had a previous cardiovascular occasion). In different phrases, docs understand round 25-fold extra profit than there really is. It is because research (practically all funded by the drug business) carry out a statistical sleight-of-hand by reporting one thing known as “relative threat’ that misrepresents and exaggerates the real benefit.
  • They’re “treating” both complete ldl cholesterol, which is a crude marker of cardiovascular threat in giant populations however nearly ineffective when utilized to assessing the chance of a person, or LDL cholestrol, a calculated—not measured—worth. Beneath the most effective of circumstances, calculated LDL ldl cholesterol is an unreliable, imprecise marker for cardiovascular threat. Introduce physiological modifications resembling grain/sugar elimination or fish oil supplementation and dramatic modifications develop within the composition of blood lipoproteins (fat-carrying proteins) that make the equation to calculate LDL ldl cholesterol much more unreliable—the truth is wildly unreliable. You possibly can witness the unreliability of calculated LDL ldl cholesterol once you carry out a superior methodology of assessing cardiovascular threat, resembling an NMR lipoprotein panel. Calculated LDL ldl cholesterol could be, for instance, 160 mg/dl—pretty excessive—however actually be solely 1000 nmol/L, the equal of an LDL worth of 100 mg/dl—the calculated worth is off by 60%. Such inaccuracies usually are not the exception, however the rule.

Throw on high of this the truth that a 3rd of working towards physicians are self-admitted control freaks and maybe it ought to come as no shock that persons are so generally bullied into statin—and different—prescriptions and medical recommendation.

Right here’s a greater solution to view statin medicine and the discount of cardiovascular threat. For those who get rid of wheat/grains and sugar, restore vitamin D standing, complement fish oil for omega-Three fatty acids, appropriate iodine deficiency and acquire preferrred thyroid standing, restore magnesium, and domesticate wholesome bowel flora, i.e., the Wheat Belly methods:

  • Small LDL particles, the commonest trigger for coronary heart illness, are dramatically decreased or eradicated
  • HDL ldl cholesterol will increase, rising from, say, a high-risk degree of 35 mg/dl, to a wholesome degree of 70-90 mg/dl over time
  • Triglycerides plummet. It isn’t unusual for a price of 350 mg/dl to drop to 45 mg/dl, an 87% discount. Because of this the real cause of heart disease, VLDL particles wealthy in triglycerides, are decreased.
  • Whole ldl cholesterol drops (although can even rise since HDL rises a lot—but one more reason why complete ldl cholesterol is nugatory: it might go up however displays the contribution of rising HDL, an excellent factor)
  • Blood sugar, HbA1c drop, insulin resistance reverses
  • Blood strain drops
  • Irritation/CRP plummet. CRP ranges of zero are typical. (And, no, you do not want high-dose statins to scale back CRP, as some statin producers and docs will argue.)

The essential lipid panel, in addition to a complicated lipoprotein panel, are remodeled with these life-style modifications, reflecting decreased cardiovascular threat—with out statin medicine.

So the true query with statin medicine turns into: Is there any incremental profit to statin medicine over and above the advantages achieved with these life-style modifications that dramatically remodel cardiovascular threat markers? If profit in folks following the incorrect food plan is 1-3%, then it’s possible that the profit to folks following the suitable food plan and life-style is way much less, maybe zero.

For essentially the most up-to-date and full model of all the Wheat Stomach program, see the total dialogue within the new Revised & Expanded Edition of Wheat Belly.



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